Chronickidneydisease(CKD)isbecomingaserioushealthproblemthroughouttheworldandisoneofthemostpotentknownrisk factorsforcardiovasculardisease,whichistheleadingcauseofmorbidityandmortalityinthispatientpopulation.Physicalinactivity has emerged as a significant and independent risk factor for accelerated deterioration of kidney function, physical function,cardiovascular function and quality of life in people in all stages of CKD. CKD specific research evidence, combined with the strong evidence on the multiple health benefits of regular and adequate amounts of PA in other cardiometabolic conditions, has resulted in physical inactivity being identified by national and international CKD clinical practice guidelines as one of the multiple

riskfactorsthatrequiresimultaneousandearlyinterventionforoptimumprevention/managementofCKD.Despitethisrealisation,physical inactivity is not systematically addressed by renal care teams. The purpose of this expert statement is therefore to inform exercise and renal care specialists about the clinical value of exercise therapy in CKD, as well as to provide some practical recommendations on how to more effectively translate the existing evidence into effective clinical practice.